Document Detail


Personalized clinical laboratory diagnostics.
MedLine Citation:
PMID:  19634778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Molecular diagnostics play an important role in development of personalized medicine and may be termed personalized diagnostics. This chapter shows the role of various diagnostic technologies in personalizing treatment. Besides polymerase chain reaction (PCR), several non-PCR methods, biochips/microarrays, and nanobiotechnologies play an important role. Technologies for biomarkers, single nucleotide polymorphisms (SNPs), and cytogenetics provide basic information for personalized medicine. Finally, integration of diagnostics with therapeutics is an important component of personalized medicine. Future challenges and prospects of personalized diagnostics are discussed.
Authors:
Kewal K Jain
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in clinical chemistry     Volume:  47     ISSN:  0065-2423     ISO Abbreviation:  Adv Clin Chem     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-28     Completed Date:  2009-08-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985173R     Medline TA:  Adv Clin Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-119     Citation Subset:  IM    
Affiliation:
Jain PharmaBiotech, Basel, Switzerland. jain@pharmabiotech.ch
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MeSH Terms
Descriptor/Qualifier:
Enzyme-Linked Immunosorbent Assay
Genetic Variation
Genome, Human
Humans
Laboratory Techniques and Procedures*
Nanotechnology
Polymerase Chain Reaction

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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