Document Detail

Persistent truncus arteriosus with dissecting aneurysm and subsequent cardiac tamponade in a lamb.
MedLine Citation:
PMID:  19564508     Owner:  NLM     Status:  MEDLINE    
The present case report describes the necropsy and histopathology findings of a 3-week-old lamb with persistent truncus arteriosus (PTA). This rare cardiac malformation was characterized by the presence of a common arterial trunk arising from the right ventricle and overriding a ventricular septal defect. The pulmonary arteries originated from a short common trunk from this PTA, which subsequently continued as the thoracic aorta. The death of the lamb was attributed to a rupture of the PTA with subsequent cardiac tamponade. Histologically, a dissecting aneurysm with elastic fiber fragmentation in the wall of the PTA was identified as the underlying pathologic condition. Altered hemodynamic forces with subsequent secondary vasculopathy, as well as congenital primary vasculopathies, should be considered as an underlying pathogenetic mechanism.
Verena Haist; Alexandra von Altrock; Andreas Beineke
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc     Volume:  21     ISSN:  1040-6387     ISO Abbreviation:  J. Vet. Diagn. Invest.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-30     Completed Date:  2009-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011490     Medline TA:  J Vet Diagn Invest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  543-6     Citation Subset:  IM    
Department of Pathology, Clinic for Swine and Small Ruminants, University of Veterinary Medicine, Buenteweg 17, D-30559 Hanover, Germany.
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MeSH Terms
Aneurysm, Dissecting / pathology,  veterinary*
Cardiac Tamponade / pathology,  veterinary*
Myocardium / pathology
Sheep Diseases / congenital*,  pathology
Truncus Arteriosus, Persistent / pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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