Document Detail


Persistent pupillary membrane, strabismus, and optic nerve hypoplasia in Donnai-Barrow syndrome.
MedLine Citation:
PMID:  22153411     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report a case of Donnai-Barrow syndrome in a 2-year-old boy who presented with exotropia and prominent eyes since birth. Ocular findings included high myopia, persistent pupillary membrane, and optic nerve hypoplasia. Facial manifestations included broad nasal bridge, hypertelorism, and downward-slanting of palpebral fissures. The patient had associated omphalocele, sensorineural hearing loss, and developmental delay. Magnetic resonance imaging revealed agenesis of the corpus callosum. To our knowledge, this is the first reported association of persistent pupillary membrane, strabismus, and optic nerve hypoplasia in a patient with Donnai-Barrow syndrome.
Authors:
Supriya Chinta; Amit Gupta; Virender Sachdeva; Ramesh Kekunnaya
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  15     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  604-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Affiliation:
LV Prasad Eye Institute, Hyderabad, India.
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