| Persistent pulmonary hypertension in preterm-infants. | |
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MedLine Citation:
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PMID: 3083387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Persistent pulmonary hypertension of the newborn (PPHN) is a cyanotic syndrome that occurs primarily in full-term and postmature infants and causes right-to-left shunts at the atrial or ductal levels or both. Term babies with PPHN show structural changes in pulmonary vascular smooth muscle as a result of chronic prenatal distress. It is our opinion that in preterm babies the PPHN syndrome also exists. In this group of patients the potential pathways to the persistence of high pulmonary vascular resistence are only functional vascular changes precipitated by acute perinatal stress. The cyanosis of PPHN is rapidly regredient in preterm infants and clinical resolution occurs promptly if the diagnosis is correct and the treatment is started as early as possible in centers capable of extensive monitoring and neonatal supportive care to minimize the risks of Tolazoline therapy. |
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Authors:
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M Amato; B de Roche; G von Muralt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pädiatrie und Pädologie Volume: 21 ISSN: 0030-9338 ISO Abbreviation: Padiatr Padol Publication Date: 1986 |
Date Detail:
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Created Date: 1986-05-16 Completed Date: 1986-05-16 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0022370 Medline TA: Padiatr Padol Country: AUSTRIA |
Other Details:
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Languages: eng Pagination: 25-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Dioxide
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blood Ductus Arteriosus, Patent / diagnosis Female Gestational Age Humans Hypertension, Pulmonary / congenital*, diagnosis Infant, Newborn Infant, Premature, Diseases / diagnosis* Male Oxygen / blood Persistent Fetal Circulation Syndrome / diagnosis Pulmonary Circulation Respiration, Artificial Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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