Document Detail

Persistent pulmonary hypertension in the neonate.
MedLine Citation:
PMID:  3277808     Owner:  NLM     Status:  MEDLINE    
Respiratory failure is the leading cause of death in the neonatal period. The anatomic and functional basis for this, particularly in full-term infants, most often is persistent pulmonary hypertension of the neonate (PPHN). This condition is reversible but can cause very severe and unrelenting respiratory failure and ultimate death when uncontrolled. Recent technologic advances have expanded the scope of therapy available for PPHN, resulting in increasing therapeutic success for these critically ill infants. This article reviews the anatomic and functional anomalies of PPHN, as well as the methods of diagnosis and discusses current treatment.
E D Graves; C R Redmond; R M Arensman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Chest     Volume:  93     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-07     Completed Date:  1988-04-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  638-41     Citation Subset:  AIM; IM    
Department of Surgery, Ochsner Clinic, New Orleans.
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MeSH Terms
Adaptation, Physiological
Combined Modality Therapy
Infant, Newborn
Persistent Fetal Circulation Syndrome / diagnosis,  physiopathology*,  therapy
Pulmonary Artery / drug effects,  physiopathology
Respiration, Artificial / methods
Vascular Resistance / drug effects
Vasodilator Agents / therapeutic use
Reg. No./Substance:
0/Vasodilator Agents

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