Document Detail


Persistent mirror movements: functional MR imaging of the hand motor cortex.
MedLine Citation:
PMID:  9114119     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To compare cortical areas involved in hand motor function in patients with persistent motor movements with those in healthy control subjects by using functional magnetic resonance (MR) imaging. MATERIALS AND METHODS: Nine patients (five patients with autosomal-dominant mirror movements, three with Kallmann syndrome, one with Wildervanck syndrome) and 10 healthy control subjects participated in the study. Functional MR imaging was performed at 1.5 T with a two-dimensional fast low-angle shot sequence. Participants were imaged while performing sequential finger-thumb opposition and during a rest period. RESULTS: During unimanual intentional movements, MR imaging in all control subjects showed increased signal intensity along the superior bend of the central sulcus contralateral to the moved hand. This increase was predominantly located in a region that included the medial part of the precentral gyrus. In contrast, MR imaging in patients with mirror movements showed bilateral activity in the medial region of the precentral gyrus. CONCLUSION: Bifurcations of the corticospinal tract may not be solely responsible for mirror movements. Bilateral activity of the primary motor cortex seems to play an additional role.
Authors:
G L Leinsinger; D T Heiss; A G Jassoy; T Pfluger; K Hahn; A Danek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  203     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-05-13     Completed Date:  1997-05-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  545-52     Citation Subset:  AIM; IM    
Affiliation:
Institute for Diagnostic Radiology, Klinikum Innenstadt, Ludwig-Maximilians-Universität Munich, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Hand / physiology*
Humans
Kallmann Syndrome / physiopathology
Klippel-Feil Syndrome / physiopathology
Magnetic Resonance Imaging*
Male
Middle Aged
Motor Cortex / physiology*
Movement Disorders / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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