Document Detail


Persistent minor smear abnormalities: is large loop excision of the transformation zone (LLETZ) the solution?
MedLine Citation:
PMID:  12963514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This prospective observational study was carried out to evaluate the efficacy of large loop excision of the transformation zone (LLETZ) as a management strategy for women with four or more smears showing borderline changes or mild dyskaryosis. A total of 102 women with four or more smears showing minor abnormalities and no colposcopic evidence of high-grade disease opted to undergo LLETZ in preference to continued cytological surveillance. Histology of the LLETZ specimens showed 11 cases of CIN2/3, one CGIN, 32 CIN1 and 10 HPV changes. In 97 of the 102 (95%) women, the follow-up cervical smear reverted to negative.
Authors:
N Pisal; M Sindos; M E Mansell; Theresa Freeman-Wang; A Singer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  23     ISSN:  0144-3615     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-09-09     Completed Date:  2003-11-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  528-30     Citation Subset:  IM    
Affiliation:
Department of Women's Health, Whittington Hospital, London, UK. pisal@dr.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cervical Intraepithelial Neoplasia / diagnosis*,  pathology,  surgery*
Female
Humans
Middle Aged
Vaginal Smears*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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