| Persistent functional atrioventricular block in two patients with prolonged QT intervals: elucidation of the mechanism of block. | |
| | |
MedLine Citation:
|
PMID: 1693199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This article describes two infants with prolonged QT interval and intermittent second-degree atrioventricular block. An asymptomatic 14-month-old child with persistent 2:1 atrioventricular conduction since birth underwent electrophysiology study including measurements with a contact monophasic action potential catheter. During 2:1 conduction, atrioventricular block occurred distal to the site of the His-bundle recording. Monophasic action potential duration was closely related to prior RR intervals. Single premature atrial or ventricular depolarizations during 1:1 conduction followed by a pause, lead to monophasic action potential prolongation and subsequent 2:1 atrioventricular conduction, which was perpetuated by the resulting long RR intervals. Paired premature ventricular contractions or short bursts of ventricular pacing elicited monophasic action potential shortening and subsequent 1:1 atrioventricular conduction that was perpetuated by the resulting short RR intervals. A second infant presented at birth with a prolonged QT interval, ventricular tachycardia, and episodes of second-degree atrioventricular block with persistent 2:1 atrioventricular conduction. The atrioventricular block was repeatedly elicited by single premature ventricular contractions and terminated by ventricular couplets. We conclude that the atrioventricular block in both patients is functional in nature and results from the interrelationships between ventricular rate, action potential duration, and His-Purkinje system refractoriness. |
| | |
Authors:
|
G F van Hare; M R Franz; C Rogé; M M Scheinman |
Related Documents
:
|
7259829 - The hyperplastic muscle columns which encroach upon the branch mouths of the coronary a... 1132089 - Electroide cather recording during malignant ventricular arrythmia following experiment... 125809 - A clinicopathological study of the heart diseases in the aged. the morphological classi... 7139899 - Electrophysiologic effects of disopyramide in patients with atrioventricular nodal dysf... 6373269 - Congenital complete heart block. 1262769 - Reassessment of q waves in left bundle branch block. 22436709 - Investigating perioperative heart migration during robot-assisted coronary artery bypas... 20108509 - Effect of angiotensin ii type 1 receptor antagonist valsartan on cardiac remodeling and... 8772739 - Prediction of recovery of myocardial dysfunction after revascularization. comparison of... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Pacing and clinical electrophysiology : PACE Volume: 13 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1990 May |
Date Detail:
|
Created Date: 1990-07-05 Completed Date: 1990-07-05 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 608-18 Citation Subset: IM |
Affiliation:
|
Cardiovascular Research Institute, University of California, San Francisco 94143. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Action Potentials
/
physiology Arrhythmias, Cardiac / complications* Electrocardiography Female Heart Block / etiology*, physiopathology Humans Infant Infant, Newborn Long QT Syndrome / complications*, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Catecholamine levels and pacing behavior of QT-driven pacemakers during exercise.
Next Document: Recurrent symptoms after ventricular pacing in unexplained syncope.