Document Detail


Persistent pleuropulmonary air leak treated with autologous blood: results from a university hospital and review of literature.
MedLine Citation:
PMID:  19556743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Persistent air leak after pulmonary resection is a difficult complication for thoracic surgeons to manage. Objectives: To show the results of our experience treating persistent pleuropulmonary air leak with autologous blood and review the literature on this specific method of treatment. METHODS: Retrospective study of patients with persistent aerial pleuropulmonary fistula treated with autologous blood. The patient's own blood was collected from a peripheral vein and directly introduced through the pleural drain. An inverted siphon was located in the drainage system to avoid prolonged clamping of the drain. This siphon impeded blood return but not air escape. RESULTS: Between January 2001 and August 2008, 27 patients were treated by the above method. Patient age ranged from 2 to 74 years, and 78% were male. Each procedure used a mean quantity of 92 ml blood. Mean persistent air leak time before pleurodesis was 10.6 days and mean time to fistula resolution after pleurodesis was 1.5 days. Twenty-three (85%) patients had persistent pleuropulmonary air leak closed with the above procedure. CONCLUSION: Treating persistent pleuropulmonary air leak with autologous blood is promising, but further studies are required to quantify its real effectiveness.
Authors:
Frederico H S Oliveira; Daniele C Cataneo; Raul L Ruiz; Antonio J M Cataneo
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-06-24
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  79     ISSN:  1423-0356     ISO Abbreviation:  Respiration     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-05     Completed Date:  2010-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  302-6     Citation Subset:  IM    
Copyright Information:
Copyright 2009 S. Karger AG, Basel.
Affiliation:
Thoracic Surgery Discipline of the Surgery and Orthopedics Department, Botucatu School of Medicine, S?o Paulo State University, S?o Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Air
Blood Transfusion, Autologous*
Child
Child, Preschool
Female
Fistula / surgery*
Humans
Lung / surgery
Male
Middle Aged
Pleura / surgery*
Pleurodesis*
Pneumothorax*
Postoperative Complications / therapy*
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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