| Persistence, suppression and re-expression of pigment formation in somatic cell hybrids between mouse melanoma cells and non-melanoma cells. | |
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MedLine Citation:
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PMID: 7263779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pigmented subtetraploid subhexaploid mouse melanoma cells were fused with a range of different cell types. Expression of pigment formation appeared to be dependent on the phenotype of the non-melanoma parent cell, so that hybrids with lymphoid cells or chick embryo erythrocytes produced pigment, but hybrids between fibroblasts or epithelial rat hepatoma cells did not. The results were independent of gene dosage of either parent cell. gamma-irradiation of suppressing partner cells prior to fusion caused progressive increase in pigmentation with increasing dose of radiation. Cybrids between cytoplasts of suppressing fibroblasts and melanoma cells were pigmented. |
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Authors:
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S Junker |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of cell science Volume: 47 ISSN: 0021-9533 ISO Abbreviation: J. Cell. Sci. Publication Date: 1981 Feb |
Date Detail:
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Created Date: 1981-10-29 Completed Date: 1981-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0052457 Medline TA: J Cell Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 207-26 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Fusion Cells, Cultured Chromosomes Cytoplasm Fibroblasts Guinea Pigs Humans Hybrid Cells / cytology* Liver Neoplasms, Experimental / ultrastructure Melanoma / ultrastructure Mice Mice, Inbred C57BL Phenotype Pigmentation* Rats |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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