Document Detail


Persistence of collateral circulation after correction of aortic coarctation.
MedLine Citation:
PMID:  3182918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The persistence of collateral circulation was evaluated one year after the correction of experimental aortic coarctation (CoA) by assessing renal perfusion with the Xenon 133-washout method and measuring distal aortic blood pressure during cross-clamping of the thoracic aorta. CoA was created in 7 puppies at 2 months of age and was corrected after a follow-up with a venous patch when the dogs were 9 months old. Two of the dogs were lost during the corrective operation due to anaesthetic complications. Four sham-operated dogs served as controls. One year after correction of CoA, four of the dogs had a pressure gradient of less than 5 mmHg at the site of CoA and one a pressure gradient of 15 mmHg. In renal perfusion measurements a mean decrease of 49% and 96% was found in the study and control groups, respectively. Blood pressures in the distal aorta decreased 47% and 83%, respectively. Two dogs in the study group had a distal blood pressure under 50 mmHg and their renal perfusion decreased markedly. Collateral circulation decreased with time after a good anatomic correction of CoA, so that one year after correction of experimental CoA about one half of the initial collateral capacity remained. This suggests that in most reoperations performed at least one year after the primary corrections, temporal shunting or a left side bypass is necessary to ensure sufficient circulation in the distal organs.
Authors:
M Tarkka; M Uhari; J Heikkilä
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  29     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1988 Sep-Oct
Date Detail:
Created Date:  1988-12-13     Completed Date:  1988-12-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  518-21     Citation Subset:  IM    
Affiliation:
Department of Surgery, University of Oulu, Finland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta / physiology
Aortic Coarctation / physiopathology,  surgery*
Blood Pressure
Collateral Circulation*
Dogs
Renal Circulation
Time Factors
Xenon Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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