Document Detail


Persistence of Candida sp. 115 during hydrolysis of penicillin G and metabolism of phenylacetic acid.
MedLine Citation:
PMID:  2486269     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The growth of Candida sp. 115 was investigated on the constituents of penicillin G hydrolysis reaction mixture. Neither penicillin G nor 6-aminopenicillanic acid was degraded or utilised for growth. The yeast accepted phenylacetic acid, sodium acetate and glucose as growth substrates. Phenylacetic acid was metabolised via p-hydroxy phenylacetic acid, which was the only accumulated metabolite. The enzymes responsible for hydroxylation of phenylacetic acid were induced by phenylacetic acid and sodium acetate.
Authors:
B S Deshpande; S S Ambedkar; V K Sudhakaran; R A Narayanan; J G Shewale
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hindustan antibiotics bulletin     Volume:  31     ISSN:  0018-1935     ISO Abbreviation:  Hindustan Antibiot Bull     Publication Date:    1989 Aug-Nov
Date Detail:
Created Date:  1991-01-24     Completed Date:  1991-01-24     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  2985097R     Medline TA:  Hindustan Antibiot Bull     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  71-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acetic Acid
Acetic Acids / metabolism
Candida / growth & development*
Culture Media
Glucose / metabolism
Hydrolysis
Penicillin G / metabolism*
Phenylacetates / metabolism*
Chemical
Reg. No./Substance:
0/Acetic Acids; 0/Culture Media; 0/Phenylacetates; 103-82-2/phenylacetic acid; 50-99-7/Glucose; 61-33-6/Penicillin G; 64-19-7/Acetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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