| Peroxisome Proliferator-Activator Receptor γ: A Link between Macrophage CD36 and Inflammation in Malaria Infection. | |
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MedLine Citation:
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PMID: 22287954 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Severe malaria infection caused by Plasmodium falciparum is a global life-threatening disease and a leading cause of death worldwide. Intensive investigations have demonstrated that macrophages play crucial roles in control of inflammatory and immune responses and clearance of Plasmodium-falciparum-parasitized erythrocytes (PE). This paper focuses on how macrophage CD36 recognizes and internalizes PE and participates the inflammatory signaling in response to Plasmodium falciparum. In addition, recent advances in our current understanding of the biological actions of PPARγ on CD36 and malaria clearance from the hosts are highlighted. |
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Authors:
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Yi Ren |
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Publication Detail:
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Type: Journal Article Date: 2012-01-11 |
Journal Detail:
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Title: PPAR research Volume: 2012 ISSN: 1687-4765 ISO Abbreviation: PPAR Res Publication Date: 2012 |
Date Detail:
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Created Date: 2012-01-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101269101 Medline TA: PPAR Res Country: United States |
Other Details:
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Languages: eng Pagination: 640769 Citation Subset: - |
Affiliation:
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W. M. Keck Center for Collaborative Neuroscience, Rutgers, the State University of New Jersey, Nelson Labs D-251, 604 Allison Road, Piscataway, NJ 08854, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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