Document Detail

Peroxidase activity in the mouse uterus, placenta and fetus during pregnancy.
MedLine Citation:
PMID:  3019349     Owner:  NLM     Status:  MEDLINE    
Changes in peroxidase activity during pregnancy were examined in CD-1 mice. Peroxidase activity was measured with guaiacol as the substrate in uterine extracts of nonpregnant mice and in uterine, placental, and fetal extracts of pregnant mice on days 9, 12, 14, 16, and 18 of gestation. Uterine peroxidase activity in nonpregnant mice was high, but declined logarithmically to only 0.2% by day 18 of pregnancy. In contrast to this decline, a concomitant 50-fold logarithmic increase in fetal peroxidase activity was observed between day 12 and 18. Activity in placental extracts did not change significantly throughout the gestational period examined. These results suggest that membrane bound peroxidase in mouse uterus and fetus undergoes major shifts during pregnancy.
J L Nelson; A P Kulkarni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biochemistry international     Volume:  13     ISSN:  0158-5231     ISO Abbreviation:  Biochem. Int.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-10-15     Completed Date:  1986-10-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8100311     Medline TA:  Biochem Int     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  131-8     Citation Subset:  IM    
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MeSH Terms
Fetus / enzymology*
Gestational Age
Isoenzymes / metabolism
Peroxidases / metabolism*
Placenta / enzymology*
Pregnancy, Animal*
Uterus / enzymology*
Reg. No./Substance:
0/Isoenzymes; EC 1.11.1.-/Peroxidases; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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