Document Detail


Pernicious anemia: what are the actual diagnosis criteria?
MedLine Citation:
PMID:  21274387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A gastric intrinsic factor output under 200 U/h after pentagastrin stimulation (N > 2000 U/h) is specific for pernicious anemia. The other findings are either variable or non specific. Serum intrinsic factor antibodies, considered as specific in general practice, are present only in half of the patients with pernicious anemia. In their absence, since the disappearance of the Schilling tests, the gastric tubage currently used for the study of gastric acid secretion, is obligatory for the simultaneous study of intrinsic factor output. This study is important to eliminate another disease much more frequent than pernicious anemia, the protein bound to cobalamin malabsorption was observed in achlorhydric simple atrophic gastritis in the presence of intrinsic factor secretion.
Authors:
Daniel Cattan
Related Documents :
6363097 - Nifedipine in the treatment of hypertension.
21327917 - Proximal and overall gastric emptying of solids in patients with reduced gastric volume...
7322327 - Intracranial pressure monitoring in severe pediatric near-drowning.
18223477 - Pharmacokinetics and pharmacodynamics of sildenafil in a patient treated with human imm...
1733747 - Preliminary assessment of the efficacy of org 6370 in photosensitive epileptic patients...
7169997 - Electromyographic findings in multiple sclerosis: remitting signs of denervation.
Publication Detail:
Type:  Comment; Letter    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  17     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-28     Completed Date:  2011-07-18     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  543-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anemia, Pernicious / diagnosis*
Female
Gastric Mucosa / metabolism
Humans
Intrinsic Factor / metabolism*
Middle Aged
Schilling Test
Chemical
Reg. No./Substance:
9008-12-2/Intrinsic Factor
Comments/Corrections
Comment On:
World J Gastroenterol. 2009 Nov 7;15(41):5121-8   [PMID:  19891010 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Isolated pancreatic granulocytic sarcoma: a case report and review of the literature.
Next Document:  A review of new atypical antipsychotic launches in the United States.