| Permethrin spot-on intoxication of cats Literature review and survey of veterinary practitioners in Australia. | |
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MedLine Citation:
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PMID: 20123482 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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FINDINGS: Of the 269 questionnaires returned, 255 were eligible for analysis. A total of 207 respondents (81%) reported cases of PSO intoxication in cats over the previous 2 years. In total, 750 individual cases were reported, with 166 deaths. While all deaths were generally attributable to intoxication, 39 cats were euthanased because owners were unable to pay the anticipated treatment costs. Brands of PSO implicated included Exelpet Flea (and Tick) Liquidator (Mars Australia) (146 respondents), Bayer Advantix (48), Purina Totalcare Flea Eliminator Line-On (19), Troy Ease-On (six) and Duogard Line-On (Virbac) (four); 67 respondents were not able to identify a specific product. Permethrin spot-on formulations were most commonly obtained from supermarkets (146 respondents), followed by pet stores (43), veterinary practices (16), and a range of other sources including produce stores and friends. The majority of intoxication cases reported involved PSOs labelled for use in dogs with specific label instructions such as 'toxic to cats'. Owners applied these PSO products to their cats accidentally or intentionally. In some cases, exposure was through secondary contact, such as when a PSO product was applied to a dog with which a cat had direct or indirect contact. RECOMMENDATIONS: In the authors' view, because of the likelihood of inappropriate use and toxicity in the non-labelled species, over-the-counter products intended for use in either dogs or cats must have a high margin of safety in all species. Furthermore, PSOs should only be available at points of sale where veterinary advice can be provided and appropriate warnings given. As an interim measure, modified labelling with more explicit warnings may reduce morbidity and mortality. |
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Authors:
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Richard Malik; Michael P Ward; Aine Seavers; Anne Fawcett; Erin Bell; Merran Govendir; Stephen Page |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of feline medicine and surgery Volume: 12 ISSN: 1532-2750 ISO Abbreviation: J. Feline Med. Surg. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-04-06 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 100897329 Medline TA: J Feline Med Surg Country: England |
Other Details:
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Languages: eng Pagination: 5-14 Citation Subset: IM |
Copyright Information:
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Copyright 2009 ESFM and AAFP. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for Veterinary Education; Faculty of Veterinary Science, The University of Sydney, Camperdown, NSW 2006, Australia. R.Malik@vetc.usyd.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Australia Cat Diseases / chemically induced*, mortality Cats Commerce / methods, standards Dose-Response Relationship, Drug Drug Labeling* Insecticides / poisoning* Permethrin / poisoning* Questionnaires Severity of Illness Index Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Insecticides; 52645-53-1/Permethrin |
| Comments/Corrections | |
Comment In:
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J Feline Med Surg. 2010 Jan;12(1):2-3
[PMID:
20123480
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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