Document Detail

Permanent iatrogenic vocal cord paralysis after I-131 therapy: a case report and literature review.
MedLine Citation:
PMID:  10885689     Owner:  NLM     Status:  MEDLINE    
A patient who underwent I-131 therapy for a solitary toxic thyroid nodule subsequently experienced vocal cord paralysis, a rare complication. The patient was examined because of hoarseness 1 week after treatment. Indirect laryngoscopy at the time confirmed right vocal cord paralysis. When the examination was repeated in 6 months, no improvement was noted; vocal cord paralysis was then declared permanent. Surprisingly, 11 months after the onset of symptoms, the patient observed improvement in her voice. At 14 months, she experienced complete vocal recovery. However, a computed tomography performed after this showed that her right vocal cord paralysis was unresolved. The apparent complete recovery of her voice is believed to be a result of adaptive compensatory mechanisms. Patients who recover from hoarseness after injury to the recurrent laryngeal nerve should have cord function documented by indirect laryngoscopy or other means before the physician performs a procedure that could harm the contralateral nerve, because damage to this nerve could result in devastating consequences.
L R Coover
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  25     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-11-03     Completed Date:  2000-11-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  508-10     Citation Subset:  IM    
Department of Medicine, Hamot Medical Center, Erie, Pennsylvania 16550, USA.
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MeSH Terms
Iatrogenic Disease*
Iodine Radioisotopes / therapeutic use*
Radiation Injuries / epidemiology*
Recurrent Laryngeal Nerve / radiation effects*
Thyroid Nodule / radiotherapy
Vocal Cord Paralysis / etiology*
Reg. No./Substance:
0/Iodine Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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