Document Detail

Periventricular leukomalacia: ultrasonic and neuropathological correlations.
MedLine Citation:
PMID:  2185115     Owner:  NLM     Status:  MEDLINE    
Ultrasound scans of a preterm neonate (27 weeks gestation) at seven weeks of age showed periventricular echo-free cavities, but these were no longer visible at 15 weeks, three weeks before the infant died. At autopsy, a linear glial scar, extending from the periventricular white-matter into the white axis of the parasagittal gyrus, was found in the area occupied by the periventricular cysts. The larger cavity was reduced to a slit-like excavation in the midst of glial tissue. Unsuspected focal infarcts in the cerebral cortex were also found. This observation demonstrates that transient echo-free cavities represent foci of cystic necrosis, which are subject to secondary collapse. In the authors' experience, the linear extension of periventricular leukomalacia (PVL) into the core of parasagittal gyri is a frequent feature of PVL, and one which cannot easily be accounted for by the usual explanations of border-zone ischaemic softening.
J Rodriguez; D Claus; G Verellen; G Lyon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  32     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-06-04     Completed Date:  1990-06-04     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  347-52     Citation Subset:  IM    
Service de Neurologie Pédiatrique, Hôpital Universitaire St. Luc, UCL, Bruxelles, Belgium.
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MeSH Terms
Brain / pathology
Encephalomalacia / diagnosis*
Infant, Newborn
Leukomalacia, Periventricular / diagnosis*,  pathology

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