| Periventricular-intraventricular haemorrhage in low-birth-weight infants at Baragwanath Hospital. | |
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MedLine Citation:
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PMID: 8197489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The prevalence of periventricular-intraventricular haemorrhage (PV-IVH) among very-low-birth-weight infants at Baragwanath Hospital has not been well documented. In this prospective study, a total of 282 live-born infants with birth weights of 1,000-1,749 g were studied over a 4 1/2-month period. Every infant had at least one cranial ultrasound examination at 7-10 days of age, while one-third of non-ventilated and all ventilated infants had ultrasound examinations on days 3, 7 and 14. Where possible, all infants had a follow-up ultrasound scan at 40 weeks' post-conceptional age. The overall prevalence of PV-IVH was 53% for infants weighing less than 1,500 g at birth and 52% for infants born at less than 35 weeks' gestation, but only 12% had either grade III or grade IV haemorrhages. The prevalence and severity of PV-IVH increased with both decreasing birth weight and decreasing gestational age and was also predicted by the need for active resuscitation at birth, mechanical ventilation and the development of pneumothorax. A total of 93% of infants without PV-IVH survived, but survival decreased with increasing grade of PV-IVH. Germinal matrix cysts were noted on follow-up in 55% of surviving infants with grade I PV-IVH. Very-low-birth-weight infants at Baragwanath Hospital therefore seem to have a higher prevalence of PV-IVH when compared with reported figures, but this is due mainly to an increase in smaller haemorrhages. |
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Authors:
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D L Sandler; P A Cooper; K D Bolton; R Y Bental; I D Simchowitz |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 84 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 1994 Jan |
Date Detail:
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Created Date: 1994-06-30 Completed Date: 1994-06-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: SOUTH AFRICA |
Other Details:
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Languages: eng Pagination: 26-9 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, University of the Witwatersrand, Johannesburg. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Hemorrhage
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epidemiology*,
etiology,
physiopathology Female Humans Infant, Low Birth Weight* Infant, Newborn Infant, Premature, Diseases / epidemiology*, etiology, physiopathology Male Prevalence Prospective Studies Risk Factors South Africa / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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