Document Detail


Peritoneal leiomyosarcomatosis originating from gastrointestinal leiomyosarcomas: CT features.
MedLine Citation:
PMID:  12649418     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the computed tomographic (CT) features of peritoneal leiomyosarcomatosis (PL) originating from gastrointestinal leiomyosarcoma and compare the CT features of primary gastrointestinal leiomyosarcomas between patients with and those without PL. MATERIALS AND METHODS: The authors reviewed the medical and surgical-pathology records and the CT scans of 89 patients with gastrointestinal leiomyosarcoma to determine the prevalence of PL. Also, the CT scans of the patients with PL were evaluated for the morphologic appearance of peritoneal lesions. The CT features of the primary tumors were compared between the patients with and those without PL. Student t and Fisher exact tests were performed. RESULTS: Metastases were present in 39 patients. PL was seen in 25 patients. Other metastatic sites included liver in 26 patients, lymph nodes in 11, lungs in three, and bone in one. In the 25 patients with PL, CT findings included multiple discrete peritoneal nodules in 22 patients and massive peritoneal lesions in three. Smudged omental infiltration was combined with other findings in 10 patients. The sites of the peritoneal masses were mesentery in 18 patients, omentum in 11, paracolic gutters in 11, pelvic cavity in eight, perihepatic space in three, and perisplenic space in one. Four patients had ascites. There were statistically significant differences in size of primary tumor (mean diameter, 12.5 cm vs 9.2 cm) (P =.01) and prevalence of exophytic growth of primary tumor (P =.02) between the patients with and those without PL. CONCLUSION: CT findings can indicate PL in the differential diagnosis. The prevalence of PL appears to be higher when it originates from large primary tumors.
Authors:
Sung Eun Rha; Hyun Kwon Ha; Ah Young Kim; Tae Kyung Kim; Byung Gil Choi; Jae Young Byun; Seung-Jae Myung; Suk-Kyun Yang
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2003-03-20
Journal Detail:
Title:  Radiology     Volume:  227     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-06     Completed Date:  2003-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  385-90     Citation Subset:  AIM; IM    
Copyright Information:
Copyright RSNA, 2003
Affiliation:
Department of Diagnostic Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap-Dong, Songpa-Ku, Seoul 138-736, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Gastrointestinal Neoplasms / pathology*
Humans
Leiomyosarcoma / radiography*,  secondary*
Male
Middle Aged
Peritoneal Neoplasms / radiography*,  secondary*
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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