Document Detail

Peritoneal dialysis solution and nutrition.
MedLine Citation:
PMID:  22652708     Owner:  NLM     Status:  In-Data-Review    
20-70% of peritoneal dialysis patients have some signs of malnutrition. Anorexia, protein and amino acid losses in dialysate, advanced age of elderly patients, inflammation and cardiac failure are among the main causes. Modern dialysis solutions aim to reduce these causes, but none of them is without side effects: glucose is relatively safe and brings additional energy but induces anorexia and lipid abnormalities, amino acids compensate dialysate losses but may increase uremia and acidosis, icodextrin helps control hyperhydration and chronic heart failure and minimizes glucose side effects, but may sometimes cause inflammation, and poly chamber bags allow the replacement of lactate by bicarbonate and are more biocompatible, decrease GDP, induce less inflammation and have a better effect on nutritional status. However, it appears that the management of nutrition with the different solutions available nowadays necessitates various combinations of solutions adapted to different patient profiles and there is not actually a single universal solution to minimize malnutrition in peritoneal dialysis patients.
Christian Verger
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Publication Detail:
Type:  Journal Article     Date:  2012-05-25
Journal Detail:
Title:  Contributions to nephrology     Volume:  178     ISSN:  1662-2782     ISO Abbreviation:  Contrib Nephrol     Publication Date:  2012  
Date Detail:
Created Date:  2012-06-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513582     Medline TA:  Contrib Nephrol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  6-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
RDPLF, Pontoise, France.
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