| Peritoneal dialysis prescription: the "Clearance Peak" model. | |
| | |
MedLine Citation:
|
PMID: 7896427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Creatinine clearance (CRCL) was studied in 20 patients on CAPD in relation to the dwell times (DT), in order to establish a personalised dialysis schedule with the best clearance (CL) results, while respecting the patient's life-style. By calculating the CRCL from the two exchanges with dwell-times of 4 and 8 hours (2 I, 2.27%), curves (2nd degree polynomial regression) were plotted with three points (0h, 4h, 8h) for CRCL and the ultrafiltration rate (UF) as a function of the DT. The DT corresponding to the CRCL peak (CLPeak-time) was calculated for each subject with the first derivative of the function. On the basis of the CRCL obtained with the three most common DT (4h, 6h, 8h), we divided the patients into three categories (CLPeak-time < 5h: "fast", 5-7h: "normal"; > 7h: "slow") for the best CRCL correspondence of the 4h, 6h or 8h exchanges respectively. Also the 8h/4h ratio was used to determine CLPeak-time. For each of the three categories there is a corresponding dialysis schedule for the best CRCL and UF results of the exchanges with DT of 4, 6 and 8 hours, plus the theoretical calculation of the daily CRCL obtainable ("fast": APD; "normal": CAPD 4 exchanges/DAPD 4 exchanges; "slow": CAPD 4 exchanges). The "CLPeak" dialysis prescription model therefore identifies the most advantageous DT for each patient by using the CRCL values of two 2.27% exchanges of 4 and 8h respectively. Functional classification into three categories may give a rational orientation to dialysis prescription in order to reach the maximum CRCL possible with the individual peritoneal transport rates. |
| | |
Authors:
|
G Virga; G Amici; G Da Rin |
Related Documents
:
|
6246187 - Synaptic relationships of the cerebral giant cells with motoneurones in the feeding sys... 9263057 - Effect of the callipyge phenotype and cooking method on tenderness of several major lam... 17520057 - Coarse particulate matter (pm2.5-10) affects heart rate variability, blood lipids, and ... 10084617 - An evaluation of the specific deterrent effects of vehicle impoundment on suspended, re... 8423757 - Exercise training alters feed efficiency and body composition in iron deficient rats. 6863097 - Effect of beta-adrenergic blockade on hyperventilation and exercise tolerance in emphys... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The International journal of artificial organs Volume: 17 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1994 Oct |
Date Detail:
|
Created Date: 1995-04-27 Completed Date: 1995-04-27 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
|
Languages: eng Pagination: 537-42 Citation Subset: IM |
Affiliation:
|
Nephrology and Dialysis Division, Regional Hospital S. Maria dei Battuti, Treviso, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Computer Simulation Creatinine / metabolism* Female Humans Life Style Male Middle Aged Models, Biological Peritoneal Dialysis, Continuous Ambulatory* Ultrafiltration Uremia / metabolism, therapy* |
| Chemical | |
Reg. No./Substance:
|
60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of approximate and iterative methods to calculate the efficiency of haemodialysis as KT/V...
Next Document: Blood compatibility of two different types of membrane oxygenator during cardiopulmonary bypass in i...