Document Detail

Peritoneal dialysis in the comprehensive management of end-stage renal disease patients with liver cirrhosis and ascites: practical aspects and review of the literature.
MedLine Citation:
PMID:  18332443     Owner:  NLM     Status:  MEDLINE    
The treatment of cirrhotic patients with ascites and end-stage renal disease is complex, due mainly to decreased effective arterial volume and hemodynamic instability. Peritoneal dialysis as a continuous therapy represents an alternative to hemodialysis-related intolerance. We report on our experience and that of others with cirrhotic patients with ascites treated by peritoneal dialysis. Hemodynamic tolerance was excellent in all patients and solute and water peritoneal transport increased to above the normal range in almost all cases. Morbidity and mortality were related principally to liver disease and other comorbidities. Peritoneal protein losses, initially high, decreased over time, maintaining serum albumin within the low normal range. The incidence of peritonitis was similar or slightly higher than usual in these patients, with peculiar etiology. The experiences with peritoneal dialysis suggest consideration of this treatment as the first choice for cirrhotic patients with ascites and that need to start dialysis.
Rafael Selgas; M-Auxiliadora Bajo; Gloria Del Peso; Rafael Sánchez-Villanueva; Elena Gonzalez; Sara Romero; Elena Olivas; Covadonga Hevia
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  28     ISSN:  0896-8608     ISO Abbreviation:  Perit Dial Int     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-03-11     Completed Date:  2008-07-07     Revised Date:  2009-06-17    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  118-22     Citation Subset:  IM    
REDinREN (Spanish Renal Research Network) and Hospital Universitario La Paz, Paseo de la Castellana 261, Madrid, Spain.
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MeSH Terms
Ascites / complications*
Catheters, Indwelling
Kidney Failure, Chronic / complications,  therapy*
Liver Cirrhosis / complications*
Nutritional Status
Peritoneal Dialysis* / adverse effects
Peritoneal Dialysis, Continuous Ambulatory
Peritonitis / etiology,  therapy
Comment In:
Perit Dial Int. 2009 Mar-Apr;29(2):236-7   [PMID:  19293365 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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