| Peritoneal Carcinomatosis in Patients With Ovarian Cancer: Enhanced CT Versus 18F-FDG PET/CT. | |
MedLine Citation:
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PMID: 23334121 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: The study aimed to evaluate the efficacy of PET/CT in detecting peritoneal carcinomatosis in patients with ovarian cancer and to compare the diagnostic accuracy of FDG PET/CT with that of enhanced abdominal CT. METHODS: The medical records of 46 consecutive patients with ovarian cancer were reviewed, and the presence of peritoneal tumor on F-FDG PET/CT and enhanced abdominal CT scans was also assessed. Imaging results were compared with the pathologic findings obtained by surgery. RESULTS: Pathologic results were positive for peritoneal carcinomatosis in 26 patients and negative in 20 patients. PET/CT correctly detected 25 of 26 patients with peritoneal carcinomatosis and enhanced abdominal CT correctly detected 23 of 26 patients. Sensitivity and specificity for the diagnosis of peritoneal carcinomatosis were 96.2% and 90%, respectively, for PET/CT and 88.5% and 65%, respectively, for enhanced abdominal CT. The accuracy of PET/CT was statistically higher than that of enhanced abdominal CT (93.5% vs 78.3%, P = 0.039). Four distinctly abnormal PET/CT findings of single nodular, multiple nodular, diffuse, and mixed FDG uptakes were identified and corresponded to pathologic findings. CONCLUSIONS: F-FDG PET/CT imaging is efficient in the diagnosis of peritoneal carcinomatosis and its performance is superior to that of enhanced abdominal CT. |
Authors:
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Hae Won Kim; Kyoung Sook Won; Seok Kil Zeon; Byeong-Cheol Ahn; Isis W Gayed |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 38 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 93-7 Citation Subset: IM |
Affiliation:
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From the *Department of Nuclear Medicine, Keimyung University School of Medicine, Daegu; †Kyungpook National University School of Medicine, Kyungpook, South Korea; and ‡Daegu, South Korea and University of Texas-Health Science Center, Houston, TX. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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