Document Detail

Peripheral signals modifying food reward.
MedLine Citation:
PMID:  22249813     Owner:  NLM     Status:  MEDLINE    
The pleasure derived from eating may feel like a simple emotion, but the decision to eat, and perhaps more importantly what to eat, involves central pathways linking energy homeostasis and reward and their regulation by metabolic and endocrine factors. Evidence is mounting that modulation of the hedonic aspects of energy balance is under the control of peripheral neuropeptides conventionally associated with homeostatic appetite control. Here, we describe the significance of reward in feeding, the neural substrates underlying the reward pathway and their modification by peptides released into the circulation from peripheral tissues.
John R W Menzies; Karolina P Skibicka; Emil Egecioglu; Gareth Leng; Suzanne L Dickson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Handbook of experimental pharmacology     Volume:  -     ISSN:  0171-2004     ISO Abbreviation:  Handb Exp Pharmacol     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-17     Completed Date:  2012-04-25     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  7902231     Medline TA:  Handb Exp Pharmacol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  131-58     Citation Subset:  IM    
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MeSH Terms
Brain / metabolism*
Energy Metabolism
Feeding Behavior*
Neural Pathways / metabolism
Neuropeptides / metabolism*
Peripheral Nervous System / metabolism*
Signal Transduction*
Reg. No./Substance:

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