Document Detail


Peripheral polyneuropathy and monoclonal gammopathy of undetermined significance.
MedLine Citation:
PMID:  2993528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prevalence of peripheral polyneuropathy in patients with monoclonal gammopathy is known to be higher than in the general population. A prevalence as high as that in the series of Osby et al, who found clinical and/or electrophysiological evidence compatible with peripheral polyneuropathy in 15 of 21 patients has not been reported before. These results could not be confirmed in a study in which 19 patients with benign monoclonal gammopathy were investigated. In contrast there were only two patients with questionable evidence of peripheral neuropathy: one had lower limb symptoms and signs only, the other had evidence of a subclinical polyneuropathy with some abnormalities of nerve conduction.
Authors:
M J Krol-v Straaten; R G Ackerstaff; C E De Maat
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  48     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-10-07     Completed Date:  1985-10-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  706-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Carpal Tunnel Syndrome / diagnosis
Electromyography
Female
Humans
Hypergammaglobulinemia / diagnosis*,  physiopathology
Immunoglobulin A / metabolism
Immunoglobulin G / metabolism
Immunoglobulin M / metabolism
Male
Median Nerve / physiopathology
Middle Aged
Motor Neurons / physiology
Polyneuropathies / diagnosis*,  physiopathology
Reaction Time / physiology
Sensation / physiology
Synaptic Transmission
Tibial Nerve / physiopathology
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M
Comments/Corrections

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