Document Detail


Peripheral oxygenation and management in the perinatal period.
MedLine Citation:
PMID:  20493790     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The mechanisms for the adequate provision of oxygen to the peripheral tissues are complex. They involve control of the microcirculation and peripheral blood flow, the position of the oxygen dissociation curve including the proportion of fetal and adult haemoglobin, blood gases and viscosity. Systemic blood pressure appears to have little effect, at least in the non-shocked state. The adequate delivery of oxygen (DO(2)) depends on consumption (VO(2)), which is variable. The balance between VO(2) and DO(2) is given by fractional oxygen extraction (FOE=VO(2)/DO(2)). FOE varies from organ to organ and with levels of activity. Measurements of FOE for the whole body produce a range of about 0.15-0.33, i.e. the body consumes 15-33% of oxygen transported.
Authors:
A Michael Weindling
Publication Detail:
Type:  Journal Article     Date:  2010-05-20
Journal Detail:
Title:  Seminars in fetal & neonatal medicine     Volume:  15     ISSN:  1878-0946     ISO Abbreviation:  Semin Fetal Neonatal Med     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101240003     Medline TA:  Semin Fetal Neonatal Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  208-15     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
University of Liverpool Neonatal Unit, Liverpool Women's Hospital, Liverpool L8 7SS, UK. a.m.weindling@liv.ac.uk
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