Document Detail


Peripheral neuropathy after multiple tetanus toxoid injections.
MedLine Citation:
PMID:  6284088     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This case documents the 14th reported patient with peripheral neuropathy following tetanus toxoid injection. A 33-year-old man developed profound mixed sensorimotor peripheral neuropathy after receiving 2 tetanus toxoid injections over a 5-month period. Periodic serial electromyographic and nerve conduction studies performed over 2 years suggested both segmental demyelination and axonal neuropathy. The patient experienced partial recovery. Analysis of this case and 13 others reported in literature indicates that in almost all cases (85%), patients had received multiple tetanus toxoid injections. Also, it appears that a prolonged interval of 14 or more days between the tetanus toxoid injection and the onset of neurological symptoms is associated with a poorer prognosis for complete recovery.
Authors:
L Reinstein; J M Pargament; J S Goodman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  63     ISSN:  0003-9993     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  1982 Jul 
Date Detail:
Created Date:  1982-08-14     Completed Date:  1982-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  332-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Electromyography
Humans
Male
Neural Conduction
Peripheral Nervous System Diseases / etiology*
Tetanus Toxoid / administration & dosage,  adverse effects*
Chemical
Reg. No./Substance:
0/Tetanus Toxoid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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