| Peripheral moving-table contrast-enhanced magnetic resonance angiography (CE-MRA) using a prototype 18-channel peripheral vascular coil and scanning parameters optimized to the patient's individual hemodynamics. | |
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MedLine Citation:
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PMID: 19388111 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To demonstrate that with a priori determination of individual patient hemodynamics, peripheral contrast-enhanced magnetic resonance angiography (pCE-MRA) can be customized to maximize signal-to noise ratio (SNR) and avoid venous enhancement. MATERIALS AND METHODS: Using a 1.5T MRI scanner and prototype 18-channel peripheral vascular (PV) coil designed for highly accelerated parallel imaging, geometry (g)-factor maps were determined. SNR-maximized protocols considering the two-dimensional sensitivity encoding (2D SENSE) factor, TE, TR, bandwidth (BW), and flip angle (FA) were precalculated and stored. For each exam, a small aortic timing bolus was performed, followed by dynamic three-dimensional (3D)-MRA of the calf. Using this information, the aorta to pedal artery and calf arteriovenous transit times were measured. This enabled estimation of the maximum upper and middle station acquisition duration to allow lower station acquisition to begin prior to venous arrival. The appropriately succinct SNR-optimized protocol for each station was selected and moving-table pCE-MRA was performed using thigh venous compression and high-relaxivity contrast material. RESULTS: The protocol was successfully applied in 15 patients and all imaging demonstrated good SNR without diagnosis-hindering venous enhancement. CONCLUSION: By knowing each patient's venous enhancement kinetics, scan parameters can be optimized to utilize maximum possible acquisition time. Some time is added for the timing scans, but in return time-resolved calf CE-MRA, maximized SNR, and decreased risk of venous enhancement are gained. |
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Authors:
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Silke Potthast; Gregory J Wilson; Maisie S Wang; Jeffrey H Maki |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 29 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-28 Completed Date: 2009-05-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1106-15 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Washington, Seattle, Washington, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arteries
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anatomy & histology*,
physiology Blood Flow Velocity / physiology Contrast Media Equipment Design Equipment Failure Analysis Humans Image Enhancement / instrumentation* Magnetic Resonance Angiography / instrumentation*, methods Magnetics / instrumentation* Male Middle Aged Motion Phantoms, Imaging Reproducibility of Results Restraint, Physical / instrumentation* Sensitivity and Specificity Transducers* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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