Document Detail


Peripheral haemodynamics in newborns: best practice guidelines.
MedLine Citation:
PMID:  20219297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Peripheral haemodynamics refers to blood flow, which determines oxygen and nutrient delivery to the tissues. Peripheral blood flow is affected by vascular resistance and blood pressure, which in turn varies with cardiac function. Arterial oxygen content depends on the blood haemoglobin concentration (Hb) and arterial pO2; tissue oxygen delivery depends on the position of the oxygen-dissociation curve, which is determined by temperature and the amount of adult or fetal haemoglobin. Methods available to study tissue perfusion include near-infrared spectroscopy, Doppler flowmetry, orthogonal polarisation spectral imaging and the peripheral perfusion index. Cardiac function, blood gases, Hb, and peripheral temperature all affect blood flow and oxygen extraction. Blood pressure appears to be less important. Other factors likely to play a role are the administration of vasoactive medications and ventilation strategies, which affect blood gases and cardiac output by changing the intrathoracic pressure.
Authors:
Michael Weindling; Fauzia Paize
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Publication Detail:
Type:  Journal Article     Date:  2010-03-09
Journal Detail:
Title:  Early human development     Volume:  86     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-07-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  159-65     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Affiliation:
School of Reproductive and Developmental Medicine, University of Liverpool, Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool, United Kingdom. a.m.weindling@liv.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Blood Circulation / physiology*
Blood Flow Velocity / physiology
Body Temperature
Hemoglobins / metabolism
Humans
Infant, Newborn / blood,  physiology*
Laser-Doppler Flowmetry / methods
Oximetry / methods
Oxygen / blood*
Practice Guidelines as Topic
Spectroscopy, Near-Infrared / methods
Viscosity
Chemical
Reg. No./Substance:
0/Hemoglobins; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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