Document Detail

Peripheral eosinophilia and respiratory symptoms in rubber injection press operators: a case-control study.
MedLine Citation:
PMID:  3740072     Owner:  NLM     Status:  MEDLINE    
To evaluate a suspected association between an outbreak of acute respiratory illness and eosinophilia and employment as a rubber worker, we performed a retrospective review of medical records of rubber workers employed from September 1983 to July 1984 in a plant housing a thermoinjection process. Twenty-five workers met the case definition of a respiratory illness requiring a physician visit. The predominant respiratory illness was acute in onset with cough, chest tightness, and dyspnea. Peripheral eosinophilia, up to 40% of white blood cells in a peripheral smear, was seen in 10 of 18 (56%) cases. Twenty-one of 25 white males with respiratory symptoms were employed in the thermoinjection process (odds ratio = 22, p less than .001). Smoking and employment in this process contributed independently to an increased risk of being a case as determined by a logistic regression analysis. Return to the plant building caused recurrence of symptoms in most cases, and these workers have been transferred or left the company. We conclude that a strong previously unrecognized association exists between employment in this neoprene rubber thermoinjection process and the development of an acute respiratory illness.
R J Thomas; R Bascom; W N Yang; J F Fisher; M E Baser; J Greenhut; J H Baker
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of industrial medicine     Volume:  9     ISSN:  0271-3586     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  1986  
Date Detail:
Created Date:  1986-09-16     Completed Date:  1986-09-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  551-9     Citation Subset:  IM    
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MeSH Terms
Bronchitis / chemically induced
Environmental Exposure
Eosinophilia / chemically induced*
Leukocyte Count
Occupational Diseases / chemically induced*
Rubber / adverse effects*
Reg. No./Substance:

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