Document Detail

Peripheral and central mechanisms regulating food intake and macronutrient selection.
MedLine Citation:
PMID:  10605906     Owner:  NLM     Status:  MEDLINE    
Food intake is regulated by a complex interaction of central and peripheral pathways. A range of neuropeptides affects feeding either through actions at the gastrointestinal/hepatic level or in the central nervous system. Circulating signals such as leptin and insulin modulate and interact with these neuropeptide systems to control energy balance. The roles of the melanocortin MC4 receptor pathway, agouti-related protein, melanocyte concentrating hormone, cocaine-amphetamine-regulated transport, neuropeptide Y, and enterostatin in the control of food intake and macronutrient selection are described.
D A York
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obesity surgery     Volume:  9     ISSN:  0960-8923     ISO Abbreviation:  Obes Surg     Publication Date:  1999 Oct 
Date Detail:
Created Date:  2000-01-24     Completed Date:  2000-01-24     Revised Date:  2007-12-05    
Medline Journal Info:
Nlm Unique ID:  9106714     Medline TA:  Obes Surg     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  471-9     Citation Subset:  IM    
Pennington Biomedical Research Center, Baton Rouge, LA 70808-4124, USA.
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MeSH Terms
Adrenal Glands / physiology
Appetite Regulation / physiology*
Brain / physiology
Eating / physiology*
Energy Metabolism / physiology*
Feeding Behavior / physiology
Hypothalamus / physiology
Leptin / metabolism*
Neuropeptides / metabolism*
Nutritive Value
Obesity / prevention & control
Peripheral Nerves / physiology
Sensitivity and Specificity
Reg. No./Substance:
0/Leptin; 0/Neuropeptides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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