Document Detail

Peripheral blood pressure measurement is as good as applanation tonometry at predicting ascending aortic blood pressure.
MedLine Citation:
PMID:  12640251     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The Sphygmocor system purports to be able to assess ascending aortic blood pressure using a transfer function. It has been shown to be accurate when data obtained invasively are used, but has not been tested prospectively using data obtained non-invasively. OBJECTIVE: To investigate the accuracy of this equipment when measurements are obtained non-invasively, as would normally be the case in the clinic setting. DESIGN AND METHODS: The study was observational. Ascending aortic pressure measurements were taken simultaneously with radial artery pressure wave recordings for estimation of ascending aortic blood pressure, in 28 patients undergoing diagnostic cardiac catheterization. RESULTS: The transfer function in the Sphygmocor system significantly underestimated invasively measured systolic blood pressure [mean -7.23 +/- 10.07 mmHg; 95% confidence interval (CI) -3.3 to -11.14 mmHg, P = 0.001] and significantly overestimated invasively measured diastolic blood pressure (mean 12.20 +/- 7.14 mmHg; 95% CI 9.43 to 14.97 mmHg, P <0.001). Oscillometrically measured brachial systolic blood pressure was not significantly different from that measured invasively in the ascending aorta (mean 3.36 +/- 10.47 mmHg; 95% CI -0.69 to 7.43 mmHg, P = 0.1), but oscillometric measurement of brachial diastolic blood pressure gave a significant overestimation of that measured invasively (mean 11.70 +/- 7.18 mmHg; 95% CI 8.91 to 14.49 mmHg, P <0.001). CONCLUSIONS The transfer function in the Sphygmocor system is no better at estimating ascending aortic blood pressure than are standard peripheral blood pressure measurements. It may be necessary to derive a new transfer system that is based on data that are acquired entirely non-invasively.
Justine I Davies; Margaret M Band; Stuart Pringle; Simon Ogston; Allan D Struthers
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  21     ISSN:  0263-6352     ISO Abbreviation:  J. Hypertens.     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-17     Completed Date:  2003-12-24     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  571-6     Citation Subset:  IM    
Department of Clinical Pharmacology, Department of Cardiology and Department of Epidemiology and Public Health, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK.
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MeSH Terms
Aorta / physiology*
Blood Pressure / physiology*
Blood Pressure Determination / instrumentation,  methods*,  statistics & numerical data
Brachial Artery / physiology
Hypertension / diagnosis,  physiopathology
Middle Aged
Radial Artery / physiology
Sphygmomanometers / statistics & numerical data
Comment In:
J Hypertens. 2003 Jul;21(7):1425-6; author reply 1426   [PMID:  12817193 ]
J Hypertens. 2003 Mar;21(3):495-6   [PMID:  12640239 ]

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