| Peripheral blood flow and oxygen extraction in the sick, newborn very low birth weight infant shortly after birth. | |
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MedLine Citation:
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PMID: 19127218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the relationship between blood pressure, peripheral blood flow (PBF), and peripheral fractional oxygen extraction (FOE). Variables that may influence PBF and peripheral FOE were also measured. Measurements of PBF by near infrared spectroscopy and fractional shortening by echocardiography were made within 12 h of birth in 24 infants less than 32 wk gestation. Blood gases, Hb, temperature, and blood pressure were also measured. PBF was significantly correlated with fractional shortening (r = 0.56, p = 0.005), Po2 (r = -0.5, p = 0.01), and peripheral temperature (r = 0.52, p = 0.01). Peripheral FOE was significantly correlated with fractional shortening (r = -0.48, p = 0.02), Po2 (r = 0.52, p = 0.02), and Pco2 (r = -0.53, p = 0.008), but not with peripheral temperature. There was no significant correlation between blood pressure and either PBF or peripheral FOE. These results indicate the importance of several physiologic variables, but not blood pressure, in determining peripheral tissue oxygen delivery in sick preterm infants receiving intensive care. It adds weight to the idea that blood pressure should not be considered a surrogate for peripheral blood flow and oxygen delivery. |
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Authors:
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Christopher M Kissack; A Michael Weindling |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric research Volume: 65 ISSN: 1530-0447 ISO Abbreviation: Pediatr. Res. Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-20 Completed Date: 2009-04-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: United States |
Other Details:
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Languages: eng Pagination: 462-7 Citation Subset: IM |
Affiliation:
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The Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, United Kingdom. chris.kissack@luht.nhs.scot.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure* Body Temperature Carbon Dioxide / blood Echocardiography Female Gestational Age Hemoglobins / metabolism Humans Infant, Newborn Infant, Premature* Infant, Very Low Birth Weight* Intensive Care, Neonatal* Linear Models Male Monitoring, Physiologic / methods Myocardial Contraction Oxygen / blood* Oxygen Consumption* Regional Blood Flow Respiration, Artificial Spectroscopy, Near-Infrared Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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