| Peripheral arterial disease: gadolinium-enhanced MR angiography versus color-guided duplex US--a meta-analysis. | |
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MedLine Citation:
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PMID: 10887229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To summarize and compare the published data on gadolinium-enhanced magnetic resonance (MR) angiography and color-guided duplex ultrasonography (US) for the work-up for peripheral arterial disease. MATERIALS AND METHODS: Studies published between January 1984 and November 1998 were included if (a) gadolinium-enhanced MR angiography and/or color-guided duplex US were performed for evaluation of arterial stenoses and occlusions in the work-up for peripheral arterial disease of the lower extremities, (b) conventional angiography was the reference standard, and (c) absolute numbers of true-positive, false-negative, true-negative, and false-positive results were available or derivable. RESULTS: With a random effects model, pooled sensitivity for MR angiography (97.5% [95% CI: 95.7%, 99.3%]) was higher than that for duplex US (87.6% [95% CI: 84.4%, 90.8%]). Pooled specificities were similar: 96.2% (95% CI: 94.4%, 97.9%) for MR angiography and 94.7% (95% CI: 93.2%, 96.2%) for duplex US. Summary receiver operating characteristic analysis demonstrated better discriminatory power for MR angiography than for duplex US. Regression coefficients for MR angiography versus US were 1.67 (95% CI: -0.23, 3.56) with adjustment for covariates, 2.11 (95% CI: 0.12, 4.09) without such adjustment, and 1.73 (95% CI: 0.44, 3.02) with a random effects model. CONCLUSION: Gadolinium-enhanced MR angiography has better discriminatory power than does color-guided duplex US and is a highly sensitive and specific method, as compared with conventional angiography, for the work-up for peripheral arterial disease. |
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Authors:
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K Visser; M G Hunink |
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Publication Detail:
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Type: Comparative Study; Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Radiology Volume: 216 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2000 Jul |
Date Detail:
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Created Date: 2000-07-27 Completed Date: 2000-07-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 67-77 Citation Subset: AIM; IM |
Affiliation:
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Departments of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Rm EE21-40a, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Contrast Media* Female Gadolinium / diagnostic use* Humans Magnetic Resonance Angiography* Male Middle Aged Peripheral Vascular Diseases / diagnosis*, ultrasonography ROC Curve Sensitivity and Specificity Ultrasonography, Doppler, Color* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 7440-54-2/Gadolinium |
| Comments/Corrections | |
Comment In:
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ACP J Club. 2001 Jan-Feb;134(1):27 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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