Document Detail

Peripheral adaptation mechanisms in physical training and cardiac rehabilitation: the case of a patient supported by a cardiowest total artificial heart.
MedLine Citation:
PMID:  21807329     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The benefits of exercise training in patients with chronic heart failure (CHF) are due to a combination of cardiac and peripheral adaptations. Separating these 2 components is normally impossible, except for patients implanted with total artificial heart (TAH), where cardiac adaptation cannot occur.
METHODS AND RESULTS: We report the case of a patient implanted with a CardioWest-TAH who underwent a comprehensive strength and endurance training program and was evaluated by repeated peak cardiopulmonary exercise tests. The patient experienced a 24% increase of peak oxygen consumption and an improvement in recovery kinetics during the training period of 29 months.
CONCLUSION: This unique situation of a patient with a TAH, and therefore a fixed peak cardiac output, allows us to isolate training-induced changes in the periphery, that suggest greater oxygen extraction and more efficient metabolic gas kinetics during the exercise and recovery phases.
Fabio Bellotto; Leonida Compostella; Piergiuseppe Agostoni; Gianluca Torregrossa; Tiziana Setzu; Antonio Gambino; Nicola Russo; Giuseppe Feltrin; Vincenzo Tarzia; Gino Gerosa
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Publication Detail:
Type:  Journal Article     Date:  2011-05-28
Journal Detail:
Title:  Journal of cardiac failure     Volume:  17     ISSN:  1532-8414     ISO Abbreviation:  J. Card. Fail.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9442138     Medline TA:  J Card Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  670-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy; Preventive Cardiology and Rehabilitation, Codivilla-Putti Institute, Cortina d'Ampezzo (BL), Italy.
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