Document Detail


Peripheral arthritis in the course of inflammatory bowel diseases.
MedLine Citation:
PMID:  20458624     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Musculoskeletal disorders are well-defined extra-intestinal manifestations of inflammatory bowel diseases (IBD). There is little data regarding the frequencies of IBD and extra-intestinal manifestations from Central and East Europe and Middle Eastern countries.
AIMS: To determine the prevalence of peripheral arthritis in IBD and to document the relationship to other extra-intestinal manifestations.
METHODS: Enrolled in the study were 357 patients who were diagnosed with IBD from December 2002 through January 2008. All of the patients underwent a detailed whole-body examination by a gastroenterologist and rheumatologist.
RESULTS: IBD-related peripheral arthritis (IBDPA) was found in 66 (18.5%) of the 357 patients (28.3% Crohn's disease, 13.5% ulcerative colitis; p=0.001 χ=11.62). IBDPA was more frequent in female patients (60.6 vs. 39.4%, p=0.000, χ=11.12). In eight (12.1%) cases, IBDPA occurred before the onset of IBD. Acute self-limiting episodes, recurrences of the attacks, and persistent symptoms of arthritis were present in 40 (60.6%), 26 (39.3%), and 29 (45.7%) patients, respectively. Arthritis was symmetrical in 33 (50%) cases. Knees (65.2%) and ankles (62.1%) were the most commonly affected joints. Erythema nodosum and pyoderma gangrenosum were more common among patients with IBDPA than patients without it (p=0.001, χ=10.49, and p=0.000 χ=25.77, respectively).
CONCLUSIONS: IBDPA is a frequent extra-intestinal complication of IBD. Those of female gender and the presence of Crohn's disease, erythema nodosum and pyoderma gangrenosum have a higher risk to develop IBDPA.
Authors:
Ilhami Yüksel; Hilmi Ataseven; Omer Başar; Seyfettin Köklü; Ibrahim Ertuğrul; Aysel Ulker; Ulkü Dağlı; Nurgül Saşmaz
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Publication Detail:
Type:  Journal Article     Date:  2010-05-11
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  56     ISSN:  1573-2568     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  2011-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  183-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Gastroenterology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey. yukselilhami@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Ankle Joint*
Arthritis / epidemiology*
Child
Colitis, Ulcerative / complications*,  epidemiology
Crohn Disease / complications*,  epidemiology
Erythema Nodosum / complications,  epidemiology
Europe / epidemiology
Female
Humans
Knee Joint*
Male
Middle Aged
Middle East / epidemiology
Prevalence
Pyoderma Gangrenosum / complications,  epidemiology
Retrospective Studies
Risk Factors
Sex Factors
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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