Document Detail

Peripartum care of the cocaine-abusing parturient: are we ready?
MedLine Citation:
PMID:  15683368     Owner:  NLM     Status:  MEDLINE    
Cocaine abuse in the United States is widespread, affecting more than 30 million people. Nearly 90% of cocaine-abusing women are of childbearing age. Cardiovascular complications of cocaine intoxication include dysrhythmias, ischemia and/or infarction, and account for most cocaine-related deaths. Pregnancy enhances the cardiovascular toxicity of cocaine. While the epidemiology, pathophysiology, clinical symptomatology and implications on pregnancy of cocaine addiction in pregnancy have received significant attention over the past 25 years, far too little attention has been given to the therapeutic considerations and peripartum care of the cocaine-abusing parturients. The timely treatment of acute cocaine-induced cardiovascular toxicity in pregnancy is by far the best predictor of good maternal and fetal outcome. However, no specific treatment guidelines are currently available for cocaine-induced cardiac dysrhythmias. This article discusses briefly several agents (and considers their mechanism of action) that have been proposed for the treatment of chest pain and other cardiovascular side-effects of cocaine toxicity in pregnancy.
Krzysztof M Kuczkowski
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  84     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-01     Completed Date:  2005-03-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  108-16     Citation Subset:  IM    
Departments of Anesthesiology and Reproductive Medicine, UCSD Medical Center, University of California-San Diego, 200 W. Arbor Drive, San Diego, CA 92103-8770, USA.
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MeSH Terms
Antidotes / therapeutic use*
Cocaine-Related Disorders / complications,  diagnosis*
Fetal Death*
Fetal Development / drug effects
Follow-Up Studies
Infant, Newborn
Maternal-Fetal Exchange
Perinatal Care / methods
Pregnancy Complications, Cardiovascular / chemically induced*,  drug therapy*
Pregnancy Outcome*
Pregnancy, High-Risk
Risk Assessment
Reg. No./Substance:

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