Document Detail

Peripartum cardiomyopathy.
MedLine Citation:
PMID:  18467806     Owner:  NLM     Status:  MEDLINE    
Peripartum cardiomyopathy (PPCM) is a rare, idiopathic, life-threatening disease of late pregnancy and early puerperium, occurring in patients with previously healthy hearts. Risk factors include multiparity, age>30 years, African American race, multiple pregnancies, obesity, hypertension, and toxemia. Signs and symptoms of PPCM resemble systolic heart failure, and it is diagnosed by exclusion. An echocardiogram typically reveals an ejection fraction of <45% and/or fractional shortening of <30%, along with a left ventricular end-diastolic dimension>2.7 cm/m2 of body surface area. Early diagnosis and treatment are important for a successful outcome. Management is similar to other forms of systolic heart failure. Patients with PPCM are at high risk of thromboembolism, and therefore anticoagulation therapy should be considered. The prognosis is variable, ranging from complete recovery, to worsening heart failure requiring cardiac transplantation, or death. Future pregnancies are often discouraged because of the high mortality rate and risk of recurrence.
Hemant K Satpathy; Donald Frey; Ruby Satpathy; Chabi Satpathy; Alfred Fleming; Syed M Mohiuddin; Jimmy Khandalavala
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medicine     Volume:  120     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-05-09     Completed Date:  2008-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  28-32     Citation Subset:  IM    
Creighton University Medical Center, 6224 S. 100 Street, Omaha, NE 68127, USA.
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MeSH Terms
Cardiomyopathy, Dilated* / diagnosis,  therapy
Pregnancy Complications, Cardiovascular* / diagnosis,  therapy
Puerperal Disorders / diagnosis,  therapy
Risk Factors

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