| Peripartum cardiomyopathy. | |
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MedLine Citation:
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PMID: 18467806 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Peripartum cardiomyopathy (PPCM) is a rare, idiopathic, life-threatening disease of late pregnancy and early puerperium, occurring in patients with previously healthy hearts. Risk factors include multiparity, age>30 years, African American race, multiple pregnancies, obesity, hypertension, and toxemia. Signs and symptoms of PPCM resemble systolic heart failure, and it is diagnosed by exclusion. An echocardiogram typically reveals an ejection fraction of <45% and/or fractional shortening of <30%, along with a left ventricular end-diastolic dimension>2.7 cm/m2 of body surface area. Early diagnosis and treatment are important for a successful outcome. Management is similar to other forms of systolic heart failure. Patients with PPCM are at high risk of thromboembolism, and therefore anticoagulation therapy should be considered. The prognosis is variable, ranging from complete recovery, to worsening heart failure requiring cardiac transplantation, or death. Future pregnancies are often discouraged because of the high mortality rate and risk of recurrence. |
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Authors:
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Hemant K Satpathy; Donald Frey; Ruby Satpathy; Chabi Satpathy; Alfred Fleming; Syed M Mohiuddin; Jimmy Khandalavala |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Postgraduate medicine Volume: 120 ISSN: 0032-5481 ISO Abbreviation: Postgrad Med Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-05-09 Completed Date: 2008-06-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: United States |
Other Details:
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Languages: eng Pagination: 28-32 Citation Subset: IM |
Affiliation:
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Creighton University Medical Center, 6224 S. 100 Street, Omaha, NE 68127, USA. kuntala@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiomyopathy, Dilated* / diagnosis, therapy Female Humans Pregnancy Pregnancy Complications, Cardiovascular* / diagnosis, therapy Prognosis Puerperal Disorders / diagnosis, therapy Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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