Document Detail

Peripartum cardiomyopathy characteristics and outcome in a tertiary care hospital.
MedLine Citation:
PMID:  20527612     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the incidence, risk factors ,maternal and foetal outcome in women with peripartum cardiomyopathy. METHODS: A descriptive study was conducted in the department of gynae obstetrics Civil Hospital, and Dow University of Health Sciences, Karachi from Oct, 2003 till Sept, 2007. Thirtytwo patients of any parity and age in their last months of pregnancy or within five months of delivery who met the criteria for diagnosis of peripartum cardiomyopathy were included in the study. Their epidemiologic data, risk factors, NYHA class and pregnancy outcomes were recorded till recovery or discharge. Analysis of results was done using descriptive analysis on SPSS version 15. RESULTS: Thirty two patients presented with PPCM, which was a frequency of 1 per 837 deliveries. The mean age was 32 +/-3 years and the mean parity 3.66 +/- 1.5. All patients were obese with mean body weight of 71.91 +/- 12.9 kg. The most frequent diagnosis of cardiomyopathy was made in 12 (37.57) Balochi and 7 (21.87) mohajir women. Twenty (62.57) presented late in post partum period and 20 (62.58) were in NYHA class IV. Chronic hypertension 10 (31.257), long term tocotysis 6 (18.757), pre-eclampsia 6 (18.757) and multiple pregnancy were main riskfactors. Eighteen (52.527) women had spontaneous vaginal delivery, 2 had assisted vaginal delivery and 2 had twin vaginal delivery. Ten (31.257) required caesarean section. The main complication was congestive cardiac failure in 20 (62.57) patients and 3 maternal deaths occurred. There were 27 live births and 5 perinatal deaths were recorded. CONCLUSION: This study showed that peripartum cardiomyopathy is associated with high morbidity and mortality. Multiple risk factors are associated with it, the most important being advancing age, parity, obesity, chronic and gestational hypertension and long term tocolysis.
Jahan Ara Hasan; Ainuddin Qureshi; Bushra Begum Ramejo; Ayesha Kamran
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  60     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-09     Completed Date:  2010-07-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  377-80     Citation Subset:  IM    
Department of Gynaecology and Obstetrics, Dow University of Health Sciences, Karachi.
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MeSH Terms
Age Factors
Cardiomyopathy, Dilated / diagnosis*,  epidemiology,  etiology
Cause of Death
Follow-Up Studies
Heart Failure
Hospitals, University
Maternal Age
Maternal Mortality
Pakistan / epidemiology
Postpartum Period
Pregnancy Complications, Cardiovascular / diagnosis*,  epidemiology,  etiology
Pregnancy Outcome*
Risk Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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