Document Detail

Peripartum cardiomyopathy and biventricular thrombi.
MedLine Citation:
PMID:  12224827     Owner:  NLM     Status:  MEDLINE    
Peripartum cardiomyopathy is a rare cardiac disorder characterized by the development of heart failure in the last month of pregnancy or up to 5 months postpartum in women without other determinable causes of cardiac failure. Intracardiac thrombi have been found at autopsy in some patients with this condition and have been demonstrated in the left or right ventricles on 2-dimensional echocardiography. A 23-year-old woman presented with peripartum cardiomyopathy and biventricular thrombi on echocardiography. The thrombi were spherical, pedunculate, shaggy and irregular in configuration, and freely mobile, suggesting that they were fresh. She was treated with conventional heart failure therapy and anticoagulants. Four days later, the apical thrombi within both ventricles had disappeared and there was no evidence of embolism on physical examination. The hypercoagulable state of the peripartum period and the severe biventricular dysfunction most likely led to the formation of biventricular thrombi.
Isao Nishi; Toshiyuki Ishimitsu; Tomoko Ishizu; Yukihiro Ueno; Akihiro Suzuki; Yoshihiro Seo; Sadanori Ohtsuka; Keiji Iida; Iwao Yamaguchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  66     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-12     Completed Date:  2003-06-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  863-5     Citation Subset:  IM    
Cardiovascular Division, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.
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MeSH Terms
Anticoagulants / therapeutic use
Cardiomyopathy, Dilated / complications*,  diagnosis,  drug therapy
Heart Septal Defects, Atrial / surgery
Puerperal Disorders / diagnosis*,  drug therapy
Thrombosis / complications*,  drug therapy,  ultrasonography
Reg. No./Substance:

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