Document Detail

Perioperative transient ischemic attack caused by the cessation of warfarin.
MedLine Citation:
PMID:  21195993     Owner:  NLM     Status:  In-Process    
This paper describes the circumstances of a patient who had been receiving long-term warfarin treatment, but ceased it prior to surgical operation, sustained a transient ischemic heart attack post-operatively, which eventuated in delayed extubation and locked-in syndrome. For patients at low risk of perioperative bleeding, anticoagulation with oral vitamin K antagonist can probably be able to maintain the therapeutic range (INR ≤ 2.0) extreme. For patients with a high risk of bleeding, the international normalized ratio (INR) should be kept ≤ 1.5. Within this range, patients at low risk of thrombosis can discontinue warfarin treatment for 2-5 days pre-operatively; patients at high risk for thrombosis can stop warfarin but should probably be treated with intravenous or subcutaneous heparin when the INR is subtherapeutic.
Sing-Ong Lee; Min-Jia Li; Hsin-Ming Ho; Chih-Cheng Chien; Shu-Lin Guo
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Publication Detail:
Type:  Journal Article     Date:  2010-12-22
Journal Detail:
Title:  Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists     Volume:  48     ISSN:  1875-452X     ISO Abbreviation:  Acta Anaesthesiol Taiwan     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101214918     Medline TA:  Acta Anaesthesiol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  188-90     Citation Subset:  IM    
Copyright Information:
Taiwan Society of Anesthesiologists, Publised by Elsevier Taiwan LLC, All rights reserved.
Department of Anesthesiology, Cathay General Hospital, Taipei, Taiwan, R.O.C.
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