| Perioperative statin use: an update. | |
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MedLine Citation:
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PMID: 21074749 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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HMG CoA reductase inhibitors (statins) are a proven modality to reduce serum cholesterol and have been shown to reduce morbidity and mortality in cardiovascular patients. Statins have also demonstrated improvements in postoperative outcomes among patients taking them in the perioperative period. Many of the studies are limited to select patient populations and/or select surgeries. This review will give an overview of the pharmacology of statins, summarize the mechanisms of the beneficial effects of statins, and provide an overview of evidence in the use of statins in the perioperative period. |
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Authors:
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Phillip L Kalarickal; Charles J Fox; Jeffrey Y Tsai; Henry Liu; Alan D Kaye |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anesthesiology clinics Volume: 28 ISSN: 1932-2275 ISO Abbreviation: Anesthesiol Clin Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101273663 Medline TA: Anesthesiol Clin Country: United States |
Other Details:
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Languages: eng Pagination: 739-51 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Anesthesiology, Tulane University Medical Center, 1430 Tulane Avenue, SL-4, New Orleans, LA 70112, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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