Document Detail

Perioperative statin use: an update.
MedLine Citation:
PMID:  21074749     Owner:  NLM     Status:  In-Process    
HMG CoA reductase inhibitors (statins) are a proven modality to reduce serum cholesterol and have been shown to reduce morbidity and mortality in cardiovascular patients. Statins have also demonstrated improvements in postoperative outcomes among patients taking them in the perioperative period. Many of the studies are limited to select patient populations and/or select surgeries. This review will give an overview of the pharmacology of statins, summarize the mechanisms of the beneficial effects of statins, and provide an overview of evidence in the use of statins in the perioperative period.
Phillip L Kalarickal; Charles J Fox; Jeffrey Y Tsai; Henry Liu; Alan D Kaye
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesiology clinics     Volume:  28     ISSN:  1932-2275     ISO Abbreviation:  Anesthesiol Clin     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101273663     Medline TA:  Anesthesiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  739-51     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Department of Anesthesiology, Tulane University Medical Center, 1430 Tulane Avenue, SL-4, New Orleans, LA 70112, USA.
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