Document Detail


Perioperative management of a patient with congenital myasthenia gravis for elective caesarean section.
MedLine Citation:
PMID:  11358192     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Congenital disorders of neuromuscular transmission are commonly referred to as congenital myasthenia gravis because of their clinical similarity to the immune-mediated disease. Differentiation between the immune-mediated and congenital forms of the disease is important, because therapy established for the former may not be appropriate for patients with the latter presentation. The course of this rare neuromuscular disorder during pregnancy and its influence on anaesthesia remain largely unknown. We report on the case of a 32-year-old parturient suffering from congenital myasthenia gravis scheduled for elective caesarean section. The perioperative management of this patient who underwent the operation under spinal anaesthesia was reviewed. The effects of anaesthetic agents and techniques on the course of congenital myasthenic patients may need further review in the light of latest findings in the electrophysiology, genetic and therapeutic studies of this syndrome.
Authors:
L K Koh; P C Ip-Yam; A S Tan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  42     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-05-18     Completed Date:  2001-06-28     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  61-3     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia & Surgical Intensive Care, Singapore General Hospital.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Spinal
Cesarean Section*
Drug Monitoring / methods
Female
Humans
Monitoring, Intraoperative / methods
Myasthenia Gravis / classification,  diagnosis,  therapy*
Perioperative Care / methods*
Postnatal Care / methods
Pregnancy
Pregnancy Complications / classification,  diagnosis,  therapy*
Pyridostigmine Bromide / therapeutic use
Surgical Procedures, Elective
Chemical
Reg. No./Substance:
101-26-8/Pyridostigmine Bromide

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