Document Detail


Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive cases.
MedLine Citation:
PMID:  22855123     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pregnancy with pulmonary hypertension is considered to be associated with increased maternal and neonatal mortality. We retrospectively reviewed all parturients with pulmonary hypertension who registered at our hospital between 1999 and December 2008. We collected information about patient characteristics, including maternal age, gravida and para, pulmonary hypertension category, New York Heart Association (NYHA) functional class, pulmonary artery pressure, mode of delivery and type of anesthesia, use of anticoagulation and advanced therapy (nitric oxide, prostacyclin analogus, bosentan or sildenafil). The overall maternal mortality was 16.7% in puerperium, and there were four fetal/neonatal deaths (13%). Logistic regression could not identify any factors, including modes of anesthesia, mode of delivery, and categories and severity of pulmonary hypertension, that were significant predictors of mortality. Maternal mortality in parturients with pulmonary hypertension is high and women with pulmonary hypertension who become pregnant warrant a multidisciplinary approach.
Authors:
Lulu Ma; Wei Liu; Yuguang Huang
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Publication Detail:
Type:  Journal Article     Date:  2012-08-02
Journal Detail:
Title:  Frontiers of medicine     Volume:  6     ISSN:  2095-0225     ISO Abbreviation:  Front Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-07     Completed Date:  2013-02-11     Revised Date:  2013-11-12    
Medline Journal Info:
Nlm Unique ID:  101549428     Medline TA:  Front Med     Country:  China    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia / methods
Chi-Square Distribution
Delivery, Obstetric / methods
Female
Fetal Death
Gestational Age
Gravidity
Humans
Hypertension, Pulmonary / mortality,  physiopathology*,  therapy*
Infant Mortality
Infant, Newborn
Logistic Models
Maternal Age
Maternal Mortality
Parity
Pregnancy
Pregnancy Complications, Cardiovascular / mortality,  physiopathology*,  therapy*
Pregnancy Outcome
Retrospective Studies
Risk
Comments/Corrections
Erratum In:
Front Med. 2013 Sep;7(3):395

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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