Document Detail

Perioperative fluid management and clinical outcomes in adults.
MedLine Citation:
PMID:  15781528     Owner:  NLM     Status:  MEDLINE    
The administration of IV fluid to avoid dehydration, maintain an effective circulating volume, and prevent inadequate tissue perfusion should be considered, along with the maintenance of sleep, pain relief, and muscular relaxation, a core element of the perioperative practice of anesthesia. Knowledge of the effects of different fluids has increased in recent years, and the choice of fluid type in a variety of clinical situations can now be rationally guided by an understanding of the physicochemical and biological properties of the various crystalloid and colloid solutions available. However, there are few useful clinical outcome data to guide this decision. Deciding how much fluid to give has historically been more controversial than choosing which fluid to use. A number of clinical studies support the notion that an approach based on administering fluids to achieve maximal left ventricular stroke volume (while avoiding excess fluid administration and consequent impairment of left ventricular performance) may improve outcomes. In this article, we review the available fluid types and strategies of fluid administration and discuss their relationship to clinical outcomes in adults.
Michael P W Grocott; Michael G Mythen; Tong J Gan
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  100     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-03-22     Completed Date:  2005-04-12     Revised Date:  2006-02-21    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1093-106     Citation Subset:  AIM; IM    
Centre for Anaesthesia, University College London, United Kingdom.
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MeSH Terms
Body Fluid Compartments / physiology
Fluid Therapy*
Perioperative Care*
Treatment Outcome
Comment In:
Anesth Analg. 2005 Nov;101(5):1561; author reply 1561   [PMID:  16244039 ]
Anesth Analg. 2006 Feb;102(2):651-2; author reply 652   [PMID:  16428590 ]

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