Document Detail

Perioperative blood pressure management with clevidipine during coiling of cerebral artery aneurysms.
MedLine Citation:
PMID:  20532109     Owner:  NLM     Status:  PubMed-not-MEDLINE    
The tight control of blood pressure (BP) is mandatory during cerebral aneurysm coiling to minimize abrupt changes in the transmural pressure across the aneurysm and thereby decrease the risk of rupture. Critical times during these procedures when significant BP changes may occur include anesthetic induction, endotracheal intubation, and emergence. Clevidipine is a recently introduced, rapidly acting dihydropyridine calcium channel antagonist. Its rapid metabolism by tissue and plasma esterases results in an effective half-life of 1 to 3 minutes. We present our preliminary experience with the use of clevidipine to control BP during the anesthetic care of three patients undergoing coiling of cerebral aneurysms in the interventional radiology suite.
Thomas Meyer; Joseph D Tobias
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi journal of anaesthesia     Volume:  3     ISSN:  0975-3125     ISO Abbreviation:  Saudi J Anaesth     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2010-06-10     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101500601     Medline TA:  Saudi J Anaesth     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  83-6     Citation Subset:  -    
Department of Anesthesiology, University of Missouri, Missouri, Colombia.
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