Document Detail

Perioperative atrial tachycardia is associated with increased mortality in infants undergoing cardiac surgery.
MedLine Citation:
PMID:  22306216     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Few data are available on the frequency or importance of perioperative atrial tachycardia in infants. We hypothesized that atrial tachycardia in infants undergoing cardiac surgery is not rare and is associated with increased morbidity and mortality. METHODS: From 2007 through 2010, 777 infants (median age, 1.8 months; interquartile range, 0.33-5.73) underwent cardiac surgery. Their medical records were reviewed for atrial tachycardia during the perioperative period. RESULTS: Of the 777 patients, 64 (8.2%) developed atrial tachycardia. The independent risk factors for developing atrial tachycardia included surgical age 6 months or younger (odds ratio, 4.4; 95% confidence interval, 1.1-19.15), use of 3 or more inotropes (odds ratio, 2.9; 95% confidence interval, 1.4-6.2), and heterotaxy syndrome (odds ratio, 2.9; 95% confidence interval, 1.1-7.4). All-cause mortality in the atrial tachycardia group was increased (21.9% vs 7.2%, P < .001) during a median follow-up period of 14.6 months (interquartile range, 6.8-24.6), and atrial tachycardia was independently associated with decreased survival (hazard ratio, 1.9; 95% confidence interval, 1.1-3.8). Infants with perioperative atrial tachycardia had a longer hospital length of stay (32 vs 17 days, P < .001) and duration of inotrope use (10.5 vs 3.0 days, P < .001). A total of 57 patients received antiarrhythmic therapy, with propranolol the most common (n = 31). Among the survivors, 48 patients received outpatient antiarrhythmic therapy, which was successfully discontinued in 23 patients at a median duration of 14 months (interquartile range, 5.7-18.6) without recurrence. CONCLUSIONS: Atrial tachycardia is common in infants undergoing cardiac surgery and is independently associated with decreased survival. Among survivors, antiarrhythmic agents successfully controlled atrial tachycardia in most patients with a low recurrence risk after discontinuation.
Pirouz Shamszad; Antonio G Cabrera; Jeffrey J Kim; Brady S Moffett; Daniel E Graves; Jeffrey S Heinle; Joseph W Rossano
Related Documents :
19042486 - Perspectives of african-american women on infant mortality.
15500816 - Experience and appraisal of worry among high worriers with and without generalized anxi...
17138296 - Young infants reach correctly in a-not-b tasks: on the development of stability and per...
7965606 - "if only i weren't" versus "if only i hadn't": distinguishing shame and guilt in counte...
20435536 - Monitoring oxygen saturation and heart rate in the early neonatal period.
24081186 - Antioxidative system in the erythrocytes of preterm neonates with sepsis: the effects o...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-3
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  -     ISSN:  1097-685X     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of institutional volumes on operative outcomes for aortic root replacement in North America.
Next Document:  A novel detachable filter to prevent thromboembolism during endovascular surgery.