Document Detail

Periodontitis and carotid atheroma: is there a causal relationship?
MedLine Citation:
PMID:  20224528     Owner:  NLM     Status:  MEDLINE    
Periodontal diseases are highly prevalent in the population. Several studies implicated that chronic periodontitis may affect the arterial wall inducing subclinical atherosclerosis by triggering a systemic inflammatory response. Three theories have been put forward to explain potential mechanisms involved: the theory of bacterial invasion, the cytokine theory and the autoimmunization theory. Periodontal inflammation could have a role in the initiation and progression of arterial diseases such as coronary artery disease and carotid atherosclerosis. Further clinical studies are required to investigate if there is a causal relationship of chronic periodontitis with echolucent unstable carotid plaques.
I D Tzorbatzoglou; G S Sfyroeras; A D Giannoukas
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  29     ISSN:  1827-1839     ISO Abbreviation:  Int Angiol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-07-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  27-9     Citation Subset:  IM    
Department of Vascular Surgery, Red Cross Hospital, Athens, Greece.
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MeSH Terms
Bacteria / immunology,  pathogenicity
Carotid Artery Diseases / etiology*,  immunology,  microbiology
Chronic Disease
Cytokines / immunology
Inflammation Mediators / immunology
Periodontitis / complications*,  immunology,  microbiology
Risk Assessment
Risk Factors
Reg. No./Substance:
0/Cytokines; 0/Inflammation Mediators

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