Document Detail


Periodontal repair in intrabony defects treated with a calcium carbonate implant and guided tissue regeneration.
MedLine Citation:
PMID:  8997677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical outcome following the concurrent use of a porous resorbable calcium carbonate (CC) implant and guided tissue regeneration (GTR) in intrabony periodontal defects was evaluated in a randomized four-treatment parallel arm study. Eighty (80) patients, each contributing one interproximal intrabony defect, were assigned to the four treatments (20 patients per treatment) including the CC implant and GTR (CC + GTR), GTR alone (GTR control), CC implant alone (CC control), and gingival flap surgery alone (GFS control). Fourteen patients treated with CC + GTR, 19 patients treated with the GTR control, 13 patients treated with the CC control, and 18 patients treated with the GFS control completed the study. Clinical healing was evaluated 6 months postsurgery and included changes in probing depth, clinical attachment level, probing bone level, and gingival recession. Postsurgery probing depth reduction was 4.5 +/- 1.7 mm (CC + GTR; P < 0.01), 4.8 +/- 1.8 mm (GTR; P < 0.01), 3.7 +/- 2.2 mm (CC; P < 0.01), and 3.3 +/- 1.6 mm (GFS; P < 0.01). Clinical attachment gain amounted to 3.3 +/- 1.4 mm (CC + GTR; P < 0.01), 4.0 +/- 2.1 mm (GTR; P < 0.01), 3.0 +/- 2.4 mm (CC; P < 0.01), and 2.0 +/- 1.7 mm (GFS; P < 0.01). The CC + GTR and GTR treatments exhibited significantly greater improvements compared to GFS (P < 0.05). Postsurgery probing bone level gain amounted to 4.0 +/- 1.7 mm (CC + GTR; P < 0.01), 4.1 +/- 1.5 mm (GTR; P < 0.01), 4.0 +/- 2.2 mm (CC; P < 0.01), and 0.5 +/- 2.0 mm (GFS; P > 0.05). The CC + GTR, GTR, and CC treatments exhibited significantly greater improvements compared to GFS (P < 0.05). Gingival recession increased significantly compared to presurgery for GTR, CC, and GFS treatments (-0.9 +/- 1.2, -0.7 +/- 0.7, and -1.2 +/- 1.4 mm, respectively; P < 0.01). The results suggest that the concurrent use of a porous resorbable CC implant and GTR has limited adjunctive effect in the treatment of intrabony periodontal defects.
Authors:
C K Kim; E J Choi; K S Cho; J K Chai; U M Wikesjö
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of periodontology     Volume:  67     ISSN:  0022-3492     ISO Abbreviation:  J. Periodontol.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-06     Completed Date:  1997-03-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1301-6     Citation Subset:  D; IM    
Affiliation:
Department of Periodontology, College of Dentistry, Yonsei University, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Alveolar Bone Loss / surgery*
Analysis of Variance
Biodegradation, Environmental
Bone Substitutes*
Calcium Carbonate*
Female
Guided Tissue Regeneration, Periodontal / methods*
Humans
Male
Middle Aged
Periodontal Pocket / surgery*
Prostheses and Implants*
Statistics, Nonparametric
Surgical Flaps
Treatment Outcome
Chemical
Reg. No./Substance:
0/Bone Substitutes; 471-34-1/Calcium Carbonate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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